CDMO SERVICES
Broad and extensive expertise
Powered by innovation, we have established expertise across a broad range of cell and gene therapy platforms:Cell Therapy
Cell Engineering
Today, cell engineering is one of the most successful applications of advanced medicine. Porton Advanced offers both autologous and allogeneic cell engineering platforms with integrated supports including CRO service, process development, analytical development, cGMP manufacturing, testing services, and regulatory assistance.
Viral Vectors
A lentivirus is a single-stranded RNA retrovirus that is widely used as a gene transfer tool in cell and gene therapies based on its ability to infect both dividing cells and differentiated non-dividing cells.
mRNA
mRNA is a promising and rapidly growing new type of advanced medicine with quick production speed, the ability to encode varied proteins, an excellent safety and efficacy profile, and flexibility in modality and formulation. We are able to provide end-to-end CRO and CDMO services.
Plasmid
As a carrier of target genes, plasmids have a significant impact on the quality, safety, and effectiveness of the gene and cell therapy final products. Our teams have years of proven experience in plasmid manufacturing, including construction optimization, colony selection, and GMP manufacturing process and analytical development.
Lentivirus Helper Plasmids
Porton Advanced has completed numerous GMP productions of plasmids, including supercoiled plasmids for LVV, AAV, and linearized plasmids for mRNA. Our facilities are equipped with level D cleanrooms for upstream fermentation, level C cleanrooms for downstream purification, and level B cleanrooms for the filling area.